Fludrocortisone 100 mcg: Uses, Dosage & Patient Guide
Table of Contents
What is Fludrocortisone 100 mcg?
Fludrocortisone 100 mcg is a synthetic corticosteroid with potent mineralocorticoid properties. It helps regulate salt and water balance in the body and is often prescribed for adrenal gland disorders such as Addison’s disease or orthostatic hypotension.
How Fludrocortisone 100 mcg Works
Fludrocortisone mimics the hormone aldosterone, which controls sodium and fluid retention. By increasing sodium reabsorption in the kidneys, it helps maintain proper blood pressure and prevents dehydration in individuals with adrenal insufficiency.
Uses of Fludrocortisone 100 mcg
Fludrocortisone 100 mcg is commonly used to treat:
- Addison’s disease – to replace low levels of corticosteroids
- Orthostatic hypotension – helps prevent sudden blood pressure drops when standing
- Congenital adrenal hyperplasia (CAH) – to manage salt-wasting
- Postural Tachycardia Syndrome (POTS) – off-label use for blood volume stabilization
Fludrocortisone 100 mcg Dosage Instructions
The dosage of Fludrocortisone 100 mcg varies by condition:
- Adults: 0.1 mg (100 mcg) once daily with food
- Children: Usually 50–100 mcg/day, based on weight and condition
Always follow your healthcare provider’s guidance. Blood pressure and electrolyte levels (especially sodium and potassium) should be monitored regularly.
Administration Tips
- Take the tablet at the same time each day
- Do not abruptly stop taking this medication
- If you miss a dose, take it as soon as you remember unless it’s near the next dose
Side Effects of Fludrocortisone 100 mcg
Like all corticosteroids, Fludrocortisone 100 mcg can cause side effects, including:
- Swelling of legs/ankles (fluid retention)
- High blood pressure
- Headache
- Hypokalemia (low potassium)
- Muscle weakness or cramping
Serious but rare side effects:
- Heart failure
- Increased intracranial pressure
- Adrenal suppression if used with other corticosteroids
Drug Interactions
Fludrocortisone 100 mcg may interact with:
- Diuretics – may worsen potassium loss
- NSAIDs – increase risk of fluid retention
- Antihypertensives – may counteract effects
- Other corticosteroids – risk of adrenal suppression
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FAQs
Can I split Fludrocortisone 100 mcg tablets?
Yes, if your doctor advises a lower dose like 50 mcg, the tablet can be halved using a pill cutter.
Is Fludrocortisone a steroid?
Yes, it is a synthetic corticosteroid with strong mineralocorticoid effects.
Can Fludrocortisone 100 mcg be used for blood pressure?
Yes, it is used to treat low blood pressure conditions like orthostatic hypotension by increasing fluid retention.
Should I stop Fludrocortisone if I feel better?
No. Continue using it as prescribed. Stopping suddenly can cause adrenal crisis, especially in Addison’s disease.
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