Description

Hydrocortisone 20 mg – Corticosteroid Tablet for Inflammation & Adrenal Support

Hydrocortisone 20 mg is a prescription corticosteroid tablet used to treat a wide range of inflammatory and autoimmune conditions, as well as hormone replacement therapy for patients with adrenal insufficiency (Addison’s disease). It mimics the body’s natural hormone cortisol and helps reduce inflammation, suppress overactive immune responses, and manage adrenal-related disorders.

As a systemic steroid, Hydrocortisone 20 mg is vital for regulating metabolism, stress response, and immune function in chronic illnesses. Its precise dosing and fast-acting nature make it a key medication in emergency and long-term therapy plans.

Uses of Hydrocortisone 20 mg

This medication is widely prescribed for:

• Adrenal Insufficiency (Addison’s Disease): Replaces deficient cortisol hormone
• Rheumatic Disorders: Rheumatoid arthritis, ankylosing spondylitis
• Severe Allergies: Asthma, allergic rhinitis, anaphylaxis (supportive)
• Skin Diseases: Severe eczema, dermatitis, psoriasis
• Autoimmune Diseases: Lupus, multiple sclerosis
• Respiratory Conditions: Sarcoidosis, COPD flares
• Gastrointestinal Disorders: Ulcerative colitis, Crohn’s disease
• Adrenal crisis management: Life-saving in stress-related cortisol deficiency

How Does Hydrocortisone Work?

Hydrocortisone is a synthetic form of cortisol—a hormone naturally produced by the adrenal glands. It works by:

• Suppressing inflammation and allergic responses
• Inhibiting the release of substances that cause immune overactivity
• Supporting metabolic and cardiovascular functions under stress
• Restoring hormone balance in cortisol-deficient states

This makes it effective in treating both chronic inflammatory conditions and acute endocrine emergencies.

Hydrocortisone 20 mg Dosage & Administration

The dosage is individualized depending on the condition and response:

• Addison’s disease: Typically 15–30 mg daily, divided into 2–3 doses
• Inflammatory diseases: 20–240 mg per day, based on severity and indication
• Stress dose: May be increased during illness, surgery, or trauma

Always take the medication with food or milk to reduce stomach upset. Do not stop abruptly—tapering is essential after long-term use.

Benefits of Hydrocortisone 20 mg

• Effective adrenal hormone replacement
• Fast relief from inflammation and allergy symptoms
• Controls immune-related damage in autoimmune diseases
• Versatile use across multiple organ systems

Possible Side Effects

Common side effects:

• Weight gain
• Insomnia
• Increased appetite
• Stomach upset
• Mood swings

Serious effects (usually with long-term or high doses):

• Osteoporosis
• High blood sugar or diabetes
• Adrenal suppression
• Glaucoma or cataracts
• Increased risk of infections

Note: Regular monitoring of blood pressure, blood sugar, eye exams, and bone health is advised during long-term therapy.

Precautions & Warnings

• Inform your doctor about existing infections, diabetes, or peptic ulcer disease
• Avoid abrupt discontinuation—follow tapering schedules
• Vaccination with live vaccines should be avoided
• May require dose adjustment in stress or illness

Drug Interactions

Hydrocortisone may interact with:

• NSAIDs (risk of stomach ulcers)
• Diabetic medications (may raise blood sugar)
• Antifungals and antibiotics (may alter steroid metabolism)
• Anticoagulants (affect INR levels)

Storage Information

• Store below 30°C in a dry place
• Keep away from direct sunlight and moisture
• Keep out of reach of children

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Conclusion

Hydrocortisone 20 mg is an essential steroid treatment for adrenal insufficiency and chronic inflammatory diseases. Its powerful anti-inflammatory and immunosuppressive effects make it a cornerstone in endocrine and autoimmune care. Use only under medical guidance for maximum benefits and safety.