Description

Pirfenex 400 mg – Advanced Antifibrotic Therapy for Pulmonary Fibrosis

Pirfenex 400 mg delivers a high-dose oral therapy of pirfenidone, a proven antifibrotic and anti-inflammatory agent used to treat idiopathic pulmonary fibrosis (IPF). This advanced dosage regimen helps more effectively slow disease progression, preserve lung function, and improve quality of life in patients with moderate-to-severe fibrosis.

By inhibiting key fibrosis-driving proteins such as transforming growth factor‑β (TGF‑β) and tumor necrosis factor‑α (TNF‑α), Pirfenex 400 mg slows collagen deposition and lung scarring, helping stabilize respiratory performance over time.

Who Is Pirfenex 400 mg For?

• Adults diagnosed with moderate-to-severe idiopathic pulmonary fibrosis
• Patients who have completed lower-dose titration (200 mg to 400 mg) and need higher antifibrotic strength
• Individuals aiming to reduce exacerbations and hospitalizations due to IPF

How Pirfenex 400 mg Works

Pirfenidone acts on multiple molecular targets to reduce inflammation, limit collagen accumulation, and interrupt fibrotic signaling—especially through the inhibition of TGF‑β and TNF‑α pathways. The 400 mg dose provides sustained lung protection and better long-term outcomes.

Key Benefits:

• More intensive inhibition of fibrotic pathways
• Potentially slower decline in lung function (measured by FVC)
• May help reduce acute exacerbations and maintain daily activities
• Well‑studied safety profile with monitoring

Dosage & Administration

• Standard dose: 400 mg three times daily with meals (total 1200 mg/day)
• A gradual titration schedule (200 → 400 mg) over 2 weeks is recommended to improve tolerance
• Swallow tablets whole with food to minimize gastrointestinal upset
• Continue treatment consistently—even if symptoms stabilize

Side Effects & Monitoring

Common side effects:

• Nausea, indigestion, stomach discomfort
• Skin rash or heightened photosensitivity
• Fatigue, dizziness
• Weight loss or appetite loss

Potential serious effects:

– Elevated liver enzymes – regular blood tests advised
– Rare lung inflammation or hepatotoxicity – monitor symptoms closely

Precautions & Contraindications

• Use with caution in patients with liver or kidney impairment—dose adjustment may be required
• Not recommended during pregnancy or breastfeeding; healthcare provider consultation essential
• Wear sun protection—photosensitivity is common
• Report any concurrent medications (e.g., ciprofloxacin, fluvoxamine, warfarin) to manage interactions

Storage Instructions

• Keep at 15–30 °C (59–86 °F)
• Store in a tightly sealed container, away from direct light and moisture
• Keep out of the reach of children

Order Pirfenex 400 mg Online at ReliableVita

Purchase authentic Pirfenex 400 mg tablets from ReliableVita.com—your trusted provider of high-dose antifibrotic therapy. A prescription is required. Ensure ongoing medical monitoring for safety and optimal results.

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