Description
Naltrexone 50 mg – Opioid & Alcohol Dependence Treatment
Naltrexone 50 mg is a prescription oral medication used in the treatment of alcohol dependence and to prevent relapse in individuals recovering from opioid addiction. As an opioid receptor antagonist, Naltrexone works by blocking the euphoric and sedative effects of opioids and alcohol in the brain, reducing cravings and helping patients stay committed to recovery.
This medication is most effective when used as part of a structured treatment program that includes counseling, lifestyle changes, and ongoing support. Unlike methadone or buprenorphine, Naltrexone is not an opioid and has no potential for abuse or dependence.
Key Uses of Naltrexone 50 mg
- Helps maintain abstinence in individuals recovering from alcohol dependence
- Prevents relapse in former opioid users after detoxification
- Reduces the rewarding effects of alcohol and opioids
- Supports long-term sobriety and recovery programs
How Naltrexone 50 mg Works
Naltrexone binds to opioid receptors in the brain and blocks the effects of opioids like heroin, morphine, and fentanyl. It also reduces the pleasurable sensations associated with alcohol, helping reduce cravings. This action discourages substance use and helps individuals avoid relapse.
Benefits:
- Non-addictive, non-opioid treatment option
- Proven to improve treatment adherence and sobriety outcomes
- Once-daily oral dosing (50 mg)
Dosage & Administration
- Usual adult dose: 50 mg once daily, orally
- Can also be administered 100 mg every other day, or 150 mg every third day (as advised by doctor)
- Start only after opioid detoxification (7–10 days opioid-free)
- Regular monitoring of liver function may be required
Who Should Use Naltrexone 50 mg?
- Individuals who have completed detoxification from opioids
- Those with a history of alcohol dependence seeking to avoid relapse
- Patients enrolled in structured rehab or support programs
Side Effects of Naltrexone
Common side effects include:
- Nausea, vomiting
- Headache
- Fatigue or drowsiness
- Abdominal pain
Severe side effects are rare but may include liver toxicity. Seek medical help if you notice yellowing of the eyes, dark urine, or persistent fatigue.
Warnings & Precautions
- Do not use if currently taking opioids or undergoing withdrawal
- Not recommended for individuals with acute hepatitis or severe liver disease
- Inform your doctor if you are pregnant or breastfeeding
- May impair reaction times—use caution when driving or operating machinery
Storage Instructions
- Store at 15°C–30°C (59°F–86°F)
- Keep away from moisture and direct sunlight
- Keep out of reach of children
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Frequently Asked Questions
What is Naltrexone 50 mg used for?
It is used to help individuals avoid relapse in alcohol dependence and opioid addiction treatment programs.
Is Naltrexone addictive?
No. Naltrexone is not an opioid and has no addictive properties.
How soon can I start Naltrexone after opioid use?
You should wait 7–10 days after your last opioid use to avoid withdrawal symptoms. Consult your doctor before starting.
Can I take Naltrexone 50 mg while drinking?
It is not recommended. Naltrexone is used to support abstinence and reduce cravings. Drinking may increase side effects.