Description
Metformin 1000 mg – Oral Antidiabetic Medication for Type 2 Diabetes
Metformin 1000 mg is a widely prescribed oral antidiabetic medication used for the management of Type 2 diabetes mellitus. It belongs to the class of drugs called biguanides, which work by reducing glucose production in the liver, improving insulin sensitivity, and enhancing glucose uptake by muscles. This helps maintain balanced blood sugar levels and reduces the risk of diabetes-related complications.
Metformin 1000 mg is often the first-line treatment for Type 2 diabetes and may be used alone or in combination with other antidiabetic medications or insulin. It is also sometimes prescribed for polycystic ovary syndrome (PCOS) to improve insulin resistance.
Uses of Metformin 1000 mg
- Control blood glucose levels in patients with Type 2 diabetes
- Improve insulin sensitivity and glucose tolerance
- Help in weight management (due to reduced appetite)
- Lower HbA1c levels
- Support metabolic health in PCOS (off-label use)
How Metformin 1000 mg Works
Metformin works primarily in the liver by inhibiting gluconeogenesis (glucose production). It also enhances peripheral insulin sensitivity and reduces intestinal absorption of glucose. Unlike some other diabetes medications, it does not cause hypoglycemia (low blood sugar) when used alone, making it a safer option for long-term therapy.
Key Benefits:
- Highly effective at lowering blood sugar levels
- Does not cause weight gain
- Supports cardiovascular health
- May lower triglycerides and LDL cholesterol
- Non-insulin-based mechanism of action
Dosage & Administration
- Standard adult dosage: 1000 mg once or twice daily with meals
- Start with a lower dose and increase gradually to minimize side effects
- Take with food to reduce gastrointestinal discomfort
- Do not crush or chew extended-release tablets
Precautions
- Not suitable for patients with severe kidney disease
- Avoid excessive alcohol while using metformin
- Inform your doctor if you’re undergoing surgery or radiologic procedures with contrast dye
- Monitor blood glucose and HbA1c levels regularly
Side Effects
Common side effects may include:
- Gastrointestinal issues: nausea, vomiting, diarrhea
- Metallic taste in the mouth
- Flatulence or stomach upset
Rare but serious side effect: lactic acidosis (seek medical help immediately if you experience muscle pain, trouble breathing, or unusual weakness).
Storage Instructions
- Store below 25°C in a dry place
- Keep out of reach of children
- Do not use expired tablets
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Frequently Asked Questions
What is Metformin 1000 mg used for?
It is used to manage blood sugar levels in people with Type 2 diabetes and may also be used off-label for PCOS-related insulin resistance.
Can I take Metformin 1000 mg twice a day?
Yes, your doctor may prescribe it once or twice daily depending on your blood sugar levels and tolerance.
Does Metformin help with weight loss?
Metformin may support modest weight loss in some patients due to appetite reduction and improved insulin sensitivity.
What are the common side effects of Metformin?
Common side effects include nausea, diarrhea, and stomach upset, especially at the start of treatment.
Is Metformin safe for long-term use?
Yes, Metformin is generally safe for long-term use under medical supervision with regular kidney function monitoring.
