Description
Afatinib 30 mg – Targeted Therapy for Advanced NSCLC
Afatinib 30 mg is a second-generation tyrosine kinase inhibitor (TKI) used to treat patients with advanced non-small cell lung cancer (NSCLC) that tests positive for EGFR (epidermal growth factor receptor) mutations. This oral medication provides a targeted approach to slowing or stopping tumor progression and is prescribed for patients who require an adjusted dose from the standard 40 mg regimen.
What Is Afatinib 30 mg?
Afatinib is approved as first-line treatment for EGFR mutation-positive NSCLC. It is available in multiple strengths, including 20 mg, 30 mg, and 40 mg, to accommodate individual patient needs. The 30 mg dosage is commonly used when patients experience side effects at higher doses or as part of a titration schedule recommended by an oncologist.
How Afatinib Works
Afatinib 30 mg works by irreversibly binding to and inhibiting tyrosine kinase receptors such as EGFR, HER2, and ErbB4. These receptors are often overactive in cancer cells, promoting uncontrolled growth and division. By blocking these proteins, Afatinib helps stop the progression of tumors and can reduce their size over time.
Unlike chemotherapy, Afatinib specifically targets cancer cell pathways, offering a more precise and less toxic treatment option for EGFR-positive patients.
Benefits of Afatinib 30 mg
- Targeted treatment for EGFR-positive NSCLC
- Alternative strength for patients sensitive to higher doses
- Convenient oral administration
- Reduces tumor size and delays disease progression
- Effective in cases resistant to first-generation TKIs
Clinical studies have shown improved progression-free survival and better quality of life in patients treated with Afatinib compared to traditional chemotherapy.
Dosage and How to Use
The standard starting dose of Afatinib is 40 mg once daily, but your healthcare provider may reduce it to 30 mg based on how you tolerate the medication.
Administration Instructions:
- Take on an empty stomach, 1 hour before or 2 hours after a meal
- Swallow the tablet whole with water
- Take at the same time each day
- Do not crush, split, or chew the tablet
Never adjust your dose without your doctor’s advice. Missed doses should be skipped if the next dose is due within 12 hours.
Possible Side Effects
Like all cancer therapies, Afatinib 30 mg may cause some side effects. The most commonly reported include:
- Diarrhea
- Skin rash or acne
- Mouth sores
- Loss of appetite
- Nail inflammation
Serious side effects, though rare, may include liver toxicity or lung inflammation. Report any unusual symptoms to your healthcare provider immediately.
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