Everything You Should Know About Apixaban Tablets 5 mg: Uses, Dosage & Precautions
Table of Contents
What is Apixaban 5 mg?
Apixaban is an oral anticoagulant (blood thinner) classified as a direct oral anticoagulant (DOAC). It inhibits Factor Xa, reducing the blood’s ability to form dangerous clots. Apixaban 5 mg is often used for stroke prevention in atrial fibrillation and to treat or prevent deep vein thrombosis (DVT) and pulmonary embolism (PE).
How Does Apixaban Work?
Apixaban works by selectively inhibiting Factor Xa, a critical component in the clotting cascade. This action prevents the conversion of prothrombin to thrombin, thus reducing the formation of blood clots. Compared to warfarin, it has fewer food/drug interactions and doesn’t require INR monitoring.
Who Should Take Apixaban 5 mg?
Apixaban 5 mg is typically prescribed for:
- Patients with non-valvular atrial fibrillation
- Individuals with DVT or PE
- Those at high risk of blood clot recurrence
In certain cases, a lower 2.5 mg dose may be used for elderly patients, those under 60 kg, or with reduced kidney function.
Apixaban 5 mg Dosage Instructions
- Take 5 mg twice daily (approximately every 12 hours)
- Can be taken with or without food
- Do not skip doses or double up on missed ones
Always follow your doctor’s instructions and take it at the same time each day for best results.
Benefits of Apixaban Tablets
- Reduces risk of stroke in AFib patients
- Effective for treating and preventing DVT/PE
- No INR or routine blood monitoring required
- Lower risk of major bleeding than warfarin
- Convenient oral dosing
Side Effects of Apixaban
Common side effects include:
- Easy bruising
- Nosebleeds or gum bleeding
- Prolonged bleeding after injury
Serious side effects (seek emergency help):
- Internal bleeding (blood in urine or stools)
- Severe headaches or dizziness (may indicate brain bleeding)
- Shortness of breath, chest pain, or coughing up blood
Warnings and Drug Interactions
- Avoid with other blood thinners unless prescribed (e.g., warfarin, heparin)
- Inform your doctor of any liver or kidney disease
- Avoid NSAIDs like ibuprofen and aspirin unless approved
- Limit or avoid alcohol and grapefruit juice
- Consult your doctor if pregnant or breastfeeding
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FAQs About Apixaban 5 mg
What is Apixaban 5 mg used for?
It is used for stroke prevention in atrial fibrillation, and to treat or prevent DVT and PE.
How often should I take Apixaban 5 mg?
It is typically taken twice daily, around 12 hours apart, with or without food.
Is Apixaban better than warfarin?
Apixaban has fewer food and drug interactions, no need for INR monitoring, and a lower risk of certain types of bleeding.
Can Apixaban be stopped suddenly?
No, stopping Apixaban suddenly increases the risk of stroke or clot recurrence. Consult your doctor before making changes.
Does Apixaban require monitoring?
No routine blood tests like INR are required. However, periodic kidney and liver function checks may be advised.
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