Leuprolide Acetate 1 mg Injection – Uses, Dosage & Complete Guide
Table of Contents
What is Leuprolide Acetate?
Leuprolide Acetate 1 mg is a gonadotropin-releasing hormone (GnRH) agonist used to regulate hormone levels. It is commonly used to treat conditions related to abnormal hormone production such as prostate cancer, endometriosis, and uterine fibroids. The injection is administered subcutaneously (under the skin) and works by decreasing estrogen and testosterone levels in the body.
How Does Leuprolide Acetate Work?
Leuprolide initially increases hormone levels, but with continuous use, it suppresses gonadotropin release from the pituitary gland. This leads to reduced levels of sex hormones like testosterone and estrogen, which helps in managing hormone-dependent conditions like prostate cancer and endometriosis.
Uses of Leuprolide Acetate 1 mg
Leuprolide Acetate 1 mg is used in the treatment of:
- Prostate cancer – Suppresses testosterone to slow cancer growth
- Endometriosis – Reduces estrogen to relieve pelvic pain and inflammation
- Uterine fibroids – Helps shrink fibroids before surgery
- Central precocious puberty (CPP) – Delays early puberty in children
- IVF and fertility protocols – Controls hormonal cycles during assisted reproduction
Recommended Dosage
The standard dose is Leuprolide Acetate 1 mg injected once daily under the skin. Your healthcare provider may adjust the dosage or frequency depending on your condition and treatment goals.
Note: Always use this injection under medical supervision and follow sterile technique during self-administration.
Possible Side Effects of Leuprolide Acetate
Common Side Effects:
- Hot flashes
- Decreased libido
- Headache
- Fatigue
- Mood changes
Serious but Rare:
- Bone thinning (osteoporosis)
- Increased blood sugar or cholesterol
- Severe allergic reaction (anaphylaxis)
Discuss any unusual symptoms with your doctor immediately.
Precautions and Warnings
- Not recommended during pregnancy or breastfeeding
- Use with caution in patients with cardiovascular disease or diabetes
- Long-term use may lead to bone density loss
Regular health monitoring (hormone levels, bone density, blood sugar) is advised for patients using Leuprolide long term.
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FAQs – Leuprolide Acetate 1 mg
Is Leuprolide a chemotherapy drug?
No. Leuprolide is a hormone therapy, not a traditional chemotherapy. It lowers hormone levels that support tumor growth.
Can Leuprolide delay menstruation?
Yes. Leuprolide reduces estrogen levels and may lead to temporary cessation of periods, especially in endometriosis treatment.
Does Leuprolide cause menopause symptoms?
Yes. Since it lowers estrogen, women may experience hot flashes, mood swings, and vaginal dryness similar to menopause.
How quickly does Leuprolide start working?
Initial hormone surge occurs in the first week, followed by hormone suppression after 2–4 weeks of daily use.