Hydroxyurea Capsules IP 500 mg – Complete User Guide, Dosage, Uses & Side Effects
Table of Contents
What is Hydroxyurea Capsules IP 500 mg?
Hydroxyurea Capsules IP 500 mg is a prescription cytotoxic (anticancer) medicine used to treat certain types of cancers and blood disorders. It is primarily indicated for chronic myeloid leukemia (CML), sickle cell anemia, and head and neck cancers.
It is categorized as an antimetabolite, which interferes with the DNA synthesis process, helping control abnormal cell growth.
Medical Uses of Hydroxyurea 500 mg
This medication is used in the management of the following conditions:
- ✅ Chronic Myeloid Leukemia (CML)
- ✅ Sickle Cell Anemia – to reduce pain episodes and the need for blood transfusions
- ✅ Head and Neck Cancers – as part of combination chemotherapy
- ✅ Polycythemia Vera and Essential Thrombocythemia
Hydroxyurea 500 mg Dosage Instructions
Dosage is highly individualized and must be prescribed by a doctor based on your condition, weight, age, and blood test results. General dosage guidance:
- For CML: Usually 20-30 mg/kg once daily
- For sickle cell anemia: 15-20 mg/kg daily or as directed
- For cancer treatment: In combination with other chemo agents as per schedule
Important: Do not chew or break the capsule. Swallow it whole with water. Always follow your oncologist or hematologist’s guidance.
How Hydroxyurea Works
Hydroxyurea works by inhibiting an enzyme needed for DNA replication in cells. This action stops the growth of cancerous or abnormally dividing cells. In sickle cell anemia, it increases fetal hemoglobin production, which reduces the formation of sickle-shaped red blood cells and decreases painful episodes.
Common and Serious Side Effects
Common Side Effects:
- Nausea, vomiting
- Loss of appetite
- Fatigue and weakness
- Skin darkening or rash
Serious Side Effects (Seek medical help):
- Low white/red blood cell counts (neutropenia, anemia)
- Mouth sores
- Fever or infection due to lowered immunity
- Liver function changes
Precautions Before Use
- Regular **blood tests** are needed to monitor your blood counts and liver function
- Not recommended in **pregnancy or breastfeeding** unless advised by your doctor
- Inform your doctor about other medications or supplements you take
- Wear gloves when handling capsules. Wash hands afterward
Where to Buy Hydroxyurea Capsules IP 500 mg Online
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FAQs – Hydroxyurea Capsules IP 500 mg
What is Hydroxyurea 500 mg used for?
It is used to treat certain cancers (like CML), blood disorders like sickle cell anemia, and manage high platelet counts.
How long can I take Hydroxyurea?
It can be taken long-term under medical supervision, especially in chronic conditions like sickle cell anemia. Regular monitoring is crucial.
Can Hydroxyurea cure cancer?
No, but it helps manage symptoms and control cell growth. It’s used as part of combination therapy in many cancers.
Can pregnant women take Hydroxyurea?
Hydroxyurea is generally not recommended during pregnancy unless the benefits outweigh the risks. Always consult your doctor.