Description
Naltrexone & Bupropion – Dual-Action Therapy for Weight Management
Naltrexone & Bupropion combine two well-established medications into a single prescription therapy designed to support weight loss and weight management in adults with obesity or overweight. Marketed under brand names like Contrave®, this combination works by affecting neural pathways that regulate appetite and cravings.
The therapy includes:
- Naltrexone – an opioid antagonist that reduces cravings and food-related rewards
- Bupropion – a norepinephrine–dopamine reuptake inhibitor (NDRI) that boosts satiety and supports mood balance
Used alongside a reduced-calorie diet and increased physical activity, this dual-action treatment helps individuals achieve greater weight loss than with lifestyle changes alone.
How Naltrexone & Bupropion Work Together
- Appetite suppression: Bupropion enhances signals that promote fullness
- Craving reduction: Naltrexone diminishes pleasure from eating high-calorie foods
- Synergistic action: The combination targets both sides of appetite control for more effective weight management
Key Benefits
- Clinically shown to produce 5%–10% body weight loss after 16 weeks
- Improves control over food cravings and binge-eating behaviors
- Contributes to better blood sugar and lipid profiles
- Helps maintain weight loss over the long term
Who Is This Therapy For?
- Adults with a BMI ≥30 kg/m² (obese)
- Adults with BMI ≥27 kg/m² with weight-related conditions (e.g., hypertension, diabetes)
- Patients committed to lifestyle changes and regular follow-up
Dosage & Administration
Initiate treatment with a gradual uptitration to reduce side effects. A typical 4‑week schedule:
- Week 1: 1 tablet in the morning (8 mg naltrexone/90 mg bupropion)
- Week 2: 2 tablets (split morning and evening)
- Weeks 3–4: 3‑4 tablets daily
- Maintenance: 2 tablets twice daily (max 32 mg/360 mg)
Take with food to reduce nausea. Monitor progress with your healthcare provider; evaluate for response at 12–16 weeks.
Possible Side Effects
- Nausea, constipation, headache
- Dizziness, insomnia, dry mouth
- Increased heart rate or blood pressure in some people
If you experience persistent or severe symptoms, consult your doctor promptly.
Precautions & Contraindications
- Not suitable for those with uncontrolled high blood pressure, seizure history, or anorexia
- Avoid in current opioid users (may precipitate withdrawal)
- Not approved for use during pregnancy or lactation
- Requires monitoring if used with other antidepressants or seizure medicines
Storage Instructions
- Store at room temperature (15–30 °C)
- Protect from moisture and direct sunlight
- Keep out of reach of children
Order Naltrexone & Bupropion Therapy Online at ReliableVita
Get authentic **Naltrexone & Bupropion** combination therapy (generic Contrave) from **ReliableVita.com**, along with expert customer support and fast shipping. A prescription is required—consult your healthcare provider to see if this weight management aid suits your needs.
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Frequently Asked Questions
How does this combination help with weight loss?
By targeting both appetite and food-related cravings, it supports greater weight loss than diet and exercise alone.
Who is a good candidate?
Adults with BMI ≥30 or BMI ≥27 with comorbidities, committed to lifestyle changes and regular follow‑up.
How long will I need to take it?
Therapy is ongoing, but response should be evaluated after 12–16 weeks to determine continuation.
Can I drive while on this medication?
Consult your doctor—some users experience dizziness or insomnia. Use caution until you know how you respond.
Are there interactions with other medications?
Yes—especially with antidepressants, seizure drugs, and opioids. Always review your medication list with your provider.
