Paxlovid

Description

Paxlovid – Oral Antiviral Treatment for Mild-to-Moderate COVID-19

Paxlovid is an FDA-approved oral antiviral therapy combining two medications—nirmatrelvir 150 mg and ritonavir 100 mg—used to treat mild-to-moderate COVID-19 in non-hospitalized adults and adolescents (≥12 years, ≥40 kg) at high risk for severe disease. Taken within five days of symptom onset, it significantly reduces hospitalization and death risks.

Why Paxlovid Is Recommended

• Block the virus’s 3-chymotrypsin-like protease (Mpro), halting replication.
• Ritonavir boosts nirmatrelvir levels for effective antiviral action.
• Oral 5‑day course with quick symptom improvement.

Effectiveness

Clinical trials observed an ~88% reduction in hospitalization or death among unvaccinated, high-risk adults when started within 5 days of symptoms.

Dosage & Administration

• Two 150 mg nirmatrelvir tablets + one 100 mg ritonavir tablet, twice daily for 5 days
• Can be taken with or without food—swallow tablets whole
• Begin treatment within 5 days of symptom onset
• Complete full 5‑day course even if symptoms improve

Who Is Eligible?

• Adults and children ≥12 years (≥40 kg) with mild-to-moderate COVID-19
• High-risk factors include age ≥50, diabetes, heart disease, obesity, immunosuppression

Side Effects & Safety

Common side effects include:

• Altered taste (dysgeusia)
• Diarrhea
• High blood pressure, muscle pain, headache

Severe effects are rare; monitor for allergic reactions or liver issues. Paxlovid is contraindicated with certain medications—inform your provider.

Precautions & Drug Interactions

• Contraindicated with drugs heavily metabolized by CYP3A (e.g., certain statins, antiarrhythmics, sedatives)
• Avoid use with untreated HIV due to ritonavir resistance risk
• Adjust dose in severe renal or hepatic impairment :contentReference[oaicite:15]{index=15}

Rebound Symptoms

“Rebound” COVID symptoms can appear 2–8 days post-treatment. These are typically mild and transient. CDC continues to support Paxlovid use :contentReference[oaicite:16]{index=16}.

Regulatory Status & Storage

• FDA-approved (May 2023) for adults; EUA for adolescents :contentReference[oaicite:17]{index=17}
• Store at 20–25 °C (68–77 °F); excursions permitted between 15–30 °C :contentReference[oaicite:18]{index=18}

Where to Buy Paxlovid

Paxlovid is prescription-only. At ReliableVita.com, we offer authentic generic alternatives—delivered fast and discreetly. Consult your provider to ensure Paxlovid is right for you.

Related Products You May Like

• Nirmatrelvir 150 & Ritonavir 100 – Generic Kit
• Molnupiravir (Molaz) 200 mg – COVID Antiviral Alternative
• Fluvir 75 mg – Influenza Antiviral